I want to ask someone if they are busy in their work

how would i say it?

This should work:

İşinle meşgul müsün?

denizli

yardimin icin tesekkur ederim

Yoğun musunuz ? 

or

İşleriniz yoğun mu ?

or

İşleriniz çok mu ?

Thankyou!

I thought that was more of a negative thing. Like are you tired of your work? Or is your work tiring (you´ve had enough)?

thank you both.

so i can use all these phrases? i h=just want to ask someone if they are busy at work(not tired)

işinde meşgul musun/musunuz?But I`m not so sure it is fully correct

I would use yoğun. I got confused with yorgun (=tired). meşgul might be OK.